I list only those books with 3,000 or more citations. Please notify me of omissions or corrections.

1. Thomas Kuhn, The Structure of Scientific Revolutions, 168,000
2. Karl Popper, The Logic of Scientific Discovery, 44,800
3. Karl Popper, Conjectures and Refutations, 27,800
4. Paul Feyerabend, Against Method, 18,400
5. Karl Popper, Objective Knowledge, 16,600
6. Peter Spirtes, Clark Glymour & Richard Scheines, Causation, Prediction, and Search, 13,000
7. Ernest Nagel, The Structure of Science, 11,000
8. Bas van Fraassen, The Scientific Image, 10,800
9. Carl Hempel, Aspects of Scientific Explanation, 10,600
10. Ian Hacking, Representing and Intervening, 9,400
11. Thomas Kuhn, The Essential Tension, 7,200
12. Helen Longino, Science as Social Knowledge, 6,800
13. Larry Laudan, Progress and its Problems, 6,700
14. Nancy Cartwright, How the Laws of Physics Lie, 6,500
15. James Woodward, Making Things Happen, 6,400
16. David Hull, Science as Process, 4,100
17. Nancy Cartwright, The Dappled World, 4,000
18. Philip Kitcher, The Advancement of Science, 3,800
19. Bas van Fraassen, Laws and Symmetry, 3,800
20. Hans Reichenbach, The Direction of Time, 3,500
21. John Dupre, The Disorder of Things, 3,400
22. Colin Howson & Peter Urbach, Scientific Reasoning: The Bayesian Approach, 3,400
23. Elliott Sober, The Nature of Selection, 3,300
24. Stathis Psillos, Scientific Realism, 3,000